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SARS-CoV-2 (COVID-19) Subunit Vaccine, Recombinant Spike Protein

Published: July 26, 2026Updated: August 30, 2026

This vaccine uses a purified, recombinant form of the SARS-CoV-2 spike protein to stimulate protective immunity against COVID-19. It is administered as a two-dose primary series, typically given several weeks apart, with additional booster doses recommended. The vaccine is approved for use in adults and adolescents to prevent symptomatic COVID-19 infection.

Quick summary

A protein subunit vaccine that delivers purified spike protein to generate immune protection against SARS-CoV-2 infection.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 30, 2026Editorial policy

Key facts at a glance

RxNorm
2606074
Generic
Sars-Cov-2 (Covid-19) Vaccine, Subunit, Recombinant Spike Protein
Class
unclassified
Brands
Nuvaxovid 2025-2026
Availability
rx
Lactation
unknown
Routes
—
Forms
prefilled syringe, suspension
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention of COVID-19 caused by SARS-CoV-2 in adults and adolescents (age varies by specific vaccine product). Used for primary vaccination series and booster doses.

Contains recombinant SARS-CoV-2 spike protein produced without use of the live virus. The protein is presented with an adjuvant to enhance immune response, training the body to recognize and fight the actual virus if exposed.

Like all vaccines, protection develops over time (typically 1-2 weeks after final primary series dose). Common side effects include injection site pain, fatigue, headache, and muscle aches. Serious allergic reactions are rare but possible. Does not contain preservatives like thimerosal. Consult current official guidelines for age indications and dosing schedules.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy