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Selamectin: A Guide for Dogs and Cats

Published: July 26, 2026Updated: August 20, 2026

Selamectin is a topical veterinary parasiticide used once a month to help control fleas, prevent heartworm infection, and treat or control certain intestinal worms. It is commonly sold under the brand name Revolution and should be used according to a veterinarian’s instructions for your pet’s weight and health.

Quick summary

Selamectin is usually applied monthly to the skin at the base of the tail. Use it only as directed by a veterinarian or pharmacist, and ask for advice before changing or stopping treatment.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

RxNorm
1044269
Generic
Selamectin
Class
unclassified
Brands
Revolution, Revolution Plus, Senergy, Revolt, Selarid, Selaspot
Availability
rx
Lactation
unknown
Routes
topical
Forms
solution
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy