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Selenium Sulfide

Published: July 26, 2026Updated: August 26, 2026

Selenium sulfide is a topical antifungal medication primarily used to treat fungal infections of the skin, particularly tinea versicolor (pityriasis versicolor). It is also commonly found in medicated shampoos for treating dandruff and seborrheic dermatitis of the scalp. The medication works by reducing the growth of yeast on the skin's surface, helping to restore normal skin appearance and reduce associated symptoms like scaling and discoloration.

Quick summary

Selenium sulfide is a topical antifungal agent used to treat tinea versicolor, dandruff, and seborrheic dermatitis by reducing yeast growth on the skin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

ATC
D01AE13
RxNorm
9793
Generic
Selenium Sulfide
Class
atc-d01
Brands
SelRx, Head & Shoulders Clinical Strength, Dandrex, Selsun Blue, Tersi Foam
Availability
otc
Pregnancy
C
Lactation
caution
Half-life (h)
0
Onset (min)
0
Duration (h)
0
Routes
topical
Forms
shampoo, lotion, foam
Regions
United States, Canada, United Kingdom, Australia, European Union
Monitoring
local skin irritation, hair discoloration

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Tinea versicolor (pityriasis versicolor), seborrheic dermatitis affecting the scalp or body, and dandruff. It helps relieve scaling, itching, and discoloration associated with these conditions.

Selenium sulfide is an antifungal and antiseborrheic agent that works by inhibiting the growth of Malassezia yeast (formerly known as Pityrosporum) on the skin surface. It also helps reduce skin cell turnover and excess oil production, addressing the underlying causes of flaking and scaling.

For topical use only; avoid contact with eyes, mucous membranes, and broken or inflamed skin. May bleach hair, eyebrows, and eyelashes as well as discolor jewelry. Should not be used during pregnancy or breastfeeding unless directed by a physician. Leave on the affected area for the prescribed time before rinsing, as directed by a healthcare provider.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy