Milbemycin Oxime
Sentinel Flavor Tabs is a monthly oral heartworm preventive medication for dogs that also provides control of fleas and intestinal parasites. The beef-flavored tablets make administration easy and are designed for regular monthly use in dogs and puppies. This prescription medication requires veterinary authorization and a heartworm test before starting treatment.
Sentinel Flavor Tabs is a monthly oral heartworm and flea preventive for dogs that contains milbemycin oxime and lufenuron.
Key facts at a glance
- RxNorm
- 1487173
- Generic
- Sentinel Flavor Tabs
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of heartworm disease caused by Dirofilaria immitis, control of flea populations by inhibiting flea egg development, and treatment and control of hookworm, roundworm, and whipworm infections in dogs.
Contains milbemycin oxime, which eliminates heartworm larvae and intestinal worms by disrupting their nerve transmission, and lufenuron, which prevents flea eggs from hatching by inhibiting chitin synthesis needed for egg development.
Must be administered monthly year-round for optimal protection. Dogs should be tested for existing heartworm infection before initiating therapy. Not for use in dogs with known hypersensitivity to the active ingredients. Side effects may include vomiting, diarrhea, lethargy, or skin reactions. Keep out of reach of cats as they may be more sensitive to the medication.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy