Milbemycin Oxime
Sentinel Spectrum is a monthly chewable tablet medication for dogs used to prevent heartworm disease and treat common intestinal parasites. It provides broad-spectrum protection against roundworms, hookworms, whipworms, and may help control flea populations. This prescription medication is administered year-round or seasonally based on veterinary recommendation.
Sentinel Spectrum is a monthly heartworm and intestinal parasite preventive medication for dogs.
Key facts at a glance
- RxNorm
- 1487094
- Generic
- Sentinel Spectrum
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevents heartworm disease caused by Dirofilaria immitis, and treats and controls intestinal parasite infections including roundworms (Toxocara canis, Toxascaris leonina), hookworms (Ancylostoma caninum, Uncinaria stenocephala), and whipworms (Trichuris vulpis). Some formulations also provide flea control.
Sentinel Spectrum combines antiparasitic agents that work systemically to eliminate parasitic larvae and adult worms. The exact mechanism varies by active ingredient, but generally involves disrupting the parasite's nervous system or energy metabolism.
This is a prescription-only medication for dogs. Heartworm testing is recommended before starting treatment. Should be given with food for optimal absorption. Not for use in cats. Some dogs may experience mild gastrointestinal effects. Consult your veterinarian for proper dosing based on your dog's weight.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy