Quetiapine
Seroquel (quetiapine) is an atypical antipsychotic medication that works by modulating dopamine and serotonin activity in the brain. It is primarily used to treat schizophrenia, bipolar disorder (both manic and depressive episodes), and as an adjunct treatment for major depressive disorder. This medication requires a prescription and should be taken exactly as directed by a healthcare provider.
Seroquel is a prescription antipsychotic used to treat schizophrenia, bipolar disorder, and depression by affecting dopamine and serotonin levels in the brain.
Key facts at a glance
- RxNorm
- 83553
- Generic
- Seroquel
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Seroquel is FDA-approved for treating schizophrenia in adults and adolescents (ages 13-17), bipolar I disorder (manic and depressive episodes) in adults and children (ages 10-17), and as an add-on treatment for major depressive disorder in adults.
Seroquel works by blocking dopamine D2 receptors and serotonin 5-HT2A receptors in the brain. It also has affinity for histamine H1, alpha-1 adrenergic, and muscarinic receptors, which contributes to its therapeutic effects and side effect profile.
Seroquel may cause drowsiness, weight gain, metabolic changes, and elevated blood sugar or cholesterol levels. It can also cause orthostatic hypotension (dizziness upon standing). Elderly patients with dementia-related psychosis should not take this medication. Do not stop taking Seroquel abruptly; dosage should be reduced gradually under medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy