Coagulation Factor VIIa
Sevenfact is a recombinant coagulation factor VIIa medication used as a bypassing agent for hemophilia patients with inhibitors. It is indicated for the treatment and on-demand control of bleeding episodes in adults and children with hemophilia A or B who have developed inhibitors to factor VIII or IX replacement therapy. The medication is administered via intravenous injection by healthcare professionals.
Sevenfact is a prescription hemophilia treatment used to control bleeding in patients with factor VIII or IX inhibitors.
Key facts at a glance
- RxNorm
- 2386866
- Generic
- Sevenfact
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sevenfact is used for the on-demand treatment and control of bleeding episodes in adult and pediatric patients with congenital hemophilia A or B with inhibitors to factor VIII or IX. It may also be used for surgical bleeding management in appropriate patients.
Sevenfact contains recombinant activated factor VII (rFVIIa). As a bypassing agent, it initiates hemostasis by activating the extrinsic pathway of the coagulation cascade, promoting clot formation at sites of injury independently of endogenous factor VIII or IX activity.
Sevenfact should be administered under the supervision of a qualified healthcare provider experienced in hemophilia management. Patients should be monitored for potential thrombotic events. It is administered via intravenous injection. Treatment should be individualized based on bleeding severity and clinical response. Patients should report any signs of allergic reactions or adverse events to their healthcare provider.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy