Silodosin
Silodosin is a selective alpha-1 adrenergic antagonist used to treat urinary symptoms associated with benign prostatic hyperplasia (BPH). It works by blocking alpha-1 receptors in the prostate and bladder, causing smooth muscle relaxation and improved urine flow.
Alpha-1 blocker that relaxes prostate and bladder muscles to relieve urinary obstruction.
Key facts at a glance
- ATC
- G04CA04
- RxNorm
- 720825
- Generic
- Silodosin
- Class
- atc-g04
- Brands
- Rapaflo
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of symptomatic benign prostatic hyperplasia (BPH) to improve urinary flow and reduce lower urinary tract symptoms.
Selectively blocks alpha-1 adrenergic receptors in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra, causing smooth muscle relaxation in these tissues and reducing urinary obstruction.
As a selective alpha-1A blocker, silodosin has less effect on blood pressure compared to non-selective alpha blockers. May cause retrograde ejaculation. Patients with cataract surgery should inform their ophthalmologist before treatment due to potential intraoperative floppy iris syndrome.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy