Guaifenesin
Siltussin is a brand-name expectorant medication used to relieve chest congestion associated with colds, respiratory infections, and allergies. Its active ingredient helps thin and loosen mucus in the airways, making it easier to clear through coughing.
Siltussin is an over-the-counter expectorant that helps relieve chest congestion by loosening and thinning mucus.
Key facts at a glance
- RxNorm
- 219906
- Generic
- Siltussin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to temporarily relieve chest congestion caused by the common cold, bronchitis, allergies, or other respiratory conditions that produce thick or stubborn mucus.
As an expectorant, Siltussin works by increasing the water content of mucus in the respiratory tract, which thins and loosens secretions, making them easier to expel through coughing.
Always follow dosage instructions on the label or as directed by a healthcare provider. Adequate fluid intake is recommended to help the medication work effectively. Consult a doctor before use if pregnant, nursing, or giving to children under specified age limits. Stop use and seek medical attention if symptoms worsen or persist beyond 7 days.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy