Silver Sulfadiazine
Silvadene is a topical antibacterial cream used to prevent and treat infections in burn wounds. Its active ingredient, silver sulfadiazine, works by releasing silver ions that kill bacteria and fungi on the skin. This medication is typically applied by healthcare professionals in hospital settings for second and third-degree burn treatment.
Silvadene is a topical antibiotic cream used to prevent and treat infections in burn wounds.
Key facts at a glance
- RxNorm
- 224926
- Generic
- Silvadene
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Silvadene is primarily used to prevent and treat bacterial and fungal infections in burn wounds, particularly second and third-degree burns. It may also be used for other skin conditions as determined by a healthcare provider.
The active ingredient silver sulfadiazine works by releasing silver ions that damage bacterial and fungal cell walls, preventing their growth and reproduction. This provides a protective antimicrobial barrier over the burned skin area.
Silvadene is for topical use only and should not be ingested. Patients with sulfa allergies should avoid this medication. Common side effects may include skin irritation, burning, or rash. Medical supervision is required for proper application and monitoring of burn wounds.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy