Sincalide
Sincalide is a synthetic hormone that mimics the action of cholecystokinin (CCK), used primarily as a diagnostic agent to stimulate gallbladder contraction and bile flow. It is administered intravenously before imaging procedures to assess gallbladder function and before procedures requiring bile drainage.
Sincalide is a diagnostic agent that stimulates gallbladder contraction and bile secretion, similar to the natural hormone cholecystokinin.
Key facts at a glance
- ATC
- V04CC03
- RxNorm
- 9800
- Generic
- Sincalide
- Class
- atc-v04
- Brands
- Kinevac
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to stimulate gallbladder contraction for diagnostic imaging, assess gallbladder emptying function, and induce bile secretion during certain diagnostic or therapeutic procedures such as endoscopic retrograde cholangiopancreatography (ERCP).
As a synthetic cholecystokinin analogue, sincalide binds to CCK receptors in the gallbladder smooth muscle, causing it to contract and release bile. It also stimulates pancreatic enzyme secretion.
Administered intravenously by healthcare professionals. May cause abdominal discomfort, cramping, or nausea. Contraindicated in patients with intestinal obstruction or acute pancreatitis. Should be used with caution in patients with known gallbladder disease.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy