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Oxymetazoline

Published: August 9, 2026Updated: August 9, 2026

Sinex Long-Acting is a topical nasal decongestant spray designed to provide extended relief from nasal congestion. The medication works by narrowing blood vessels in the nasal passages, reducing swelling and inflammation that causes stuffiness. It is typically used by adults and children over a certain age experiencing temporary congestion from colds, allergies, or sinus pressure.

Quick summary

Sinex Long-Acting is a nasal spray that relieves stuffiness by constricting blood vessels in the nose for temporary congestion relief.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 9, 2026Editorial policy

Key facts at a glance

RxNorm
219922
Generic
Sinex Long-Acting
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves nasal congestion associated with the common cold, hay fever, or other upper respiratory allergies, as well as sinus congestion and pressure.

The active ingredient oxymetazoline is an alpha-adrenergic agonist that constricts blood vessels in the nasal passages, reducing swelling and mucus production to allow for easier breathing.

For topical nasal use only. Do not exceed recommended duration (typically 3 days max) to avoid rebound congestion (rhinitis medicamentosa). Not recommended for treating chronic nasal congestion. Consult a healthcare provider before use if you have heart disease, high blood pressure, diabetes, or thyroid problems.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy