Acyclovir
Sitavig is a prescription antiviral medication delivered as a buccal tablet that is applied to the upper gum. It contains the active ingredient acyclovir and is specifically indicated for the treatment of recurrent herpes simplex labialis (cold sores) in adults. The medication works locally at the site of application to reduce the duration and severity of cold sore outbreaks.
Sitavig is a prescription buccal tablet containing acyclovir used to treat recurrent cold sores by reducing the duration and severity of outbreaks.
Key facts at a glance
- RxNorm
- 1493270
- Generic
- Sitavig
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sitavig is indicated for the treatment of recurrent herpes simplex labialis (cold sores) in immunocompetent adults.
Sitavig contains acyclovir, an antiviral that inhibits viral DNA replication by blocking DNA polymerase, preventing the herpes simplex virus from multiplying and spreading.
The tablet is applied to the upper gum area (canine fossa) and should not be chewed, swallowed, or crushed. Common side effects may include mild local reactions at the application site. Patients should avoid touching or repositioning the tablet after placement. This is a prescription medication that should be used under the guidance of a healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy