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Tedizolid

Published: August 9, 2026Updated: August 9, 2026

Sivextro (tedizolid) is an oxazolidinone-class antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI), including those caused by resistant bacteria like MRSA. It is effective against Gram-positive organisms and is available in both intravenous and oral formulations. The medication is typically prescribed when other antibiotics are not appropriate or have failed.

Quick summary

Sivextro is an antibiotic used to treat serious skin infections, including MRSA, available as an oral or IV medication.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 9, 2026Editorial policy

Key facts at a glance

RxNorm
1540863
Generic
Sivextro
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Sivextro is FDA-approved for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA). It is used in adult patients when other treatment options are not suitable.

Sivextro belongs to the oxazolidinone class of antibiotics. It works by binding to the bacterial 23S ribosomal RNA of the 50S subunit, inhibiting bacterial protein synthesis, which prevents the bacteria from multiplying and spreading.

Sivextro may cause serious side effects including myelosuppression (low blood cell counts), peripheral neuropathy, and Clostridioides difficile-associated diarrhea. It may interact with serotonergic medications and should be used with caution in patients with certain medical conditions. Treatment duration is typically 6 days under medical supervision.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy