Risankizumab
Skyrizi (risankizumab) is a prescription biologic medication used to treat certain autoimmune conditions, primarily moderate to severe plaque psoriasis, psoriatic arthritis, and inflammatory bowel diseases like Crohn's disease and ulcerative colitis. It works by targeting and blocking a specific protein (interleukin-23) involved in inflammation, helping to reduce the overactive immune response that causes symptoms.
Skyrizi is an IL-23 inhibitor biologic used to treat autoimmune conditions like psoriasis, psoriatic arthritis, and inflammatory bowel disease by reducing inflammation.
Key facts at a glance
- RxNorm
- 2166138
- Generic
- Skyrizi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis in adults.
A monoclonal antibody that selectively binds to and blocks interleukin-23 (IL-23), a cytokine that plays a key role in the inflammatory process of autoimmune diseases, thereby reducing inflammation and symptoms.
Administered as a subcutaneous injection. May increase risk of infections. Requires monitoring by a healthcare provider. Not recommended during pregnancy. Patients should be screened for tuberculosis before starting treatment. Common side effects include upper respiratory infections, headache, and fatigue.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy