Diphenhydramine
Sleep-Eze is an over-the-counter (OTC) sleep aid designed for adults who have occasional difficulty falling asleep. It typically contains an antihistamine as its active ingredient, which produces a sedative effect to help users initiate sleep.
Sleep-Eze is an OTC sleep aid used to help adults fall asleep when experiencing occasional sleeplessness.
Key facts at a glance
- RxNorm
- 1092744
- Generic
- Sleep-Eze
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sleep-Eze is indicated for the temporary relief of occasional sleeplessness in adults. It is not intended for regular daily use or for treating chronic insomnia.
The active ingredient (typically an antihistamine) blocks histamine receptors in the brain, reducing wakefulness and promoting drowsiness to help facilitate the onset of sleep.
For use only occasionally, not for extended periods. May cause drowsiness the next morning. Avoid alcohol and operating machinery until you know how the medication affects you. Consult a healthcare provider before use if pregnant, nursing, taking other medications, or having underlying health conditions. Not recommended for children under 12 without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy