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Insulin Glargine and Lixisenatide

Published: July 26, 2026Updated: July 26, 2026

Soliqua is a prescription medication that combines insulin glargine and lixisenatide to help manage blood sugar levels in adults with type 2 diabetes. It is used when other diabetes medications have not provided adequate glycemic control. The medication is administered as a once-daily injection.

Quick summary

Soliqua is an injectable combination medication for adults with type 2 diabetes that helps improve blood sugar control.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
1858996
Generic
Soliqua
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Soliqua is indicated for the treatment of type 2 diabetes mellitus in adults when single-agent therapy with either insulin glargine or a GLP-1 receptor agonist has not achieved adequate glycemic control.

Soliqua combines two active ingredients: insulin glargine (a long-acting insulin analog) that provides steady blood sugar control throughout the day, and lixisenatide (a GLP-1 receptor agonist) that stimulates insulin secretion, suppresses glucagon, and slows gastric emptying.

Soliqua should not be used for type 1 diabetes or diabetic ketoacidosis. Common side effects may include hypoglycemia, nausea, diarrhea, and injection site reactions. Patients should rotate injection sites and monitor blood glucose regularly. Dosage is individualized and initiated based on prior therapy.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy