Solriamfetol
Solriamfetol is a wakefulness-promoting medication used to treat excessive daytime sleepiness in adults with narcolepsy or obstructive sleep apnea. It works by affecting dopamine and norepinephrine reuptake in the brain, though its exact mechanism for improving wakefulness is not fully understood. This medication helps patients stay awake during the day but does not treat the underlying sleep disorders or replace other therapies like CPAP for sleep apnea.
Solriamfetol is a prescription wakefulness agent for adults with narcolepsy or sleep apnea who experience excessive daytime sleepiness.
Key facts at a glance
- ATC
- N06BA14
- RxNorm
- 2121751
- Generic
- Solriamfetol
- Class
- atc-n06
- Brands
- Sunosi
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea (OSA) in adults. For OSA, it is used alongside other therapies such as continuous positive airway pressure (CPAP) treatment.
The exact mechanism is unclear, but solriamfetol appears to improve wakefulness through dopamine and norepinephrine reuptake inhibition, increasing levels of these neurotransmitters in the brain.
May increase blood pressure and heart rate; monitoring is recommended. Common side effects include headache, nausea, and anxiety. Not a substitute for sleep apnea treatment. Avoid taking near bedtime due to wakefulness effects. Schedule IV controlled substance with potential for dependence.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy