Sotagliflozin
Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2 used to treat Type 2 diabetes by preventing glucose reabsorption in the kidneys and intestines.
A dual-action diabetes medication that lowers blood sugar by blocking glucose reabsorption in the kidneys and absorption in the intestines.
Key facts at a glance
- ATC
- A10BK06
- RxNorm
- 2638675
- Generic
- Sotagliflozin
- Class
- atc-a10
- Brands
- Inpefa
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to improve glycemic control in adults with Type 2 diabetes mellitus, typically as an adjunct to diet and exercise when other treatments are insufficient.
Inhibits SGLT2 in the kidneys to reduce glucose and sodium reabsorption, promoting urinary glucose excretion; inhibits SGLT1 in the intestines to reduce dietary glucose absorption. These combined actions lower blood glucose levels and may reduce cardiac preload and afterload.
Common side effects include genital mycotic infections and urinary tract infections. Associated with increased risk of diabetic ketoacidosis. Not recommended for use in Type 1 diabetes or severe renal impairment. Patients should be monitored for volume depletion and hypotension.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy