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Sofosbuvir

Published: July 26, 2026Updated: July 26, 2026

Sovaldi is a prescription brand-name medication containing the active ingredient sofosbuvir, a direct-acting antiviral agent used to treat chronic hepatitis C virus (HCV) infection. It is typically used in combination with other antiviral medications and is indicated for multiple genotypes of hepatitis C. This medication requires a valid prescription from a healthcare provider.

Quick summary

Sovaldi is a direct-acting antiviral used in combination therapy to treat chronic hepatitis C infection.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
1484917
Generic
Sovaldi
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Sovaldi is used to treat chronic hepatitis C virus (HCV) infection in adults and children. It may be used for multiple HCV genotypes and is often prescribed as part of combination therapy with other antiviral medications. Treatment decisions are made by healthcare providers based on individual patient factors.

Sovaldi contains sofosbuvir, which is a nucleotide analog inhibitor. It works by targeting the NS5B RNA-dependent RNA polymerase, an enzyme essential for the hepatitis C virus to replicate. By inhibiting this enzyme, the medication helps reduce the viral load in the body.

Sovaldi is a prescription-only medication that should be used under medical supervision. It is not a standalone treatment and is typically combined with other antivirals. Common side effects may include fatigue, headache, and nausea. Patients should inform their healthcare provider of all medications and medical conditions before starting treatment. Efficacy varies based on genotype and prior treatment history.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy