Ketorolac
Sprix is a brand-name nasal spray containing the NSAID ketorolac tromethamine, used for the short-term management of moderate to moderately severe pain when opioid analgesics are not appropriate. It provides an alternative route of administration for patients who may have difficulty taking oral pain medications.
Sprix is a prescription NSAID nasal spray for short-term moderate pain relief.
Key facts at a glance
- RxNorm
- 992421
- Generic
- Sprix
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Short-term management of moderate to moderately severe pain, typically used when other analgesics are not suitable or sufficient. It is not intended for long-term use due to risks associated with prolonged NSAID therapy.
As an NSAID, it works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins that contribute to pain, inflammation, and fever.
This medication carries black box warnings regarding cardiovascular and gastrointestinal risks. It is contraindicated for peri-operative pain in coronary artery bypass graft surgery. Use is limited to short-term therapy (typically 5 days or less) due to risk of serious adverse effects including bleeding and kidney damage. Patients should use the lowest effective dose for the shortest duration.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy