Sodium Sulfadiazine
SSD (Silver Sulfadiazine) is a topical antibacterial cream used primarily to prevent and treat bacterial infections in burn wounds. It contains silver, which has antimicrobial properties that help protect damaged skin from infection. This medication is typically applied to second and third-degree burns by healthcare professionals.
Topical antibacterial cream used to prevent and treat infections in burn wounds.
Key facts at a glance
- RxNorm
- 219770
- Generic
- Ssd
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention and treatment of bacterial infections in second and third-degree burn wounds. May also be used for other skin conditions as determined by a healthcare provider.
Silver sulfadiazine works by releasing silver ions that have antimicrobial activity against a broad range of bacteria and some fungi. The sulfonamide component also provides antibacterial effects by inhibiting bacterial folic acid synthesis.
For topical use only. May cause skin irritation, discoloration, or allergic reactions in some patients. Not recommended for use during pregnancy near term, in premature infants, or in newborns due to risk of kernicterus. Medical supervision is required for proper application and monitoring.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy