Olodaterol and Tiotropium
Stiolto is a brand-name inhalation spray combining two bronchodilators—tiotropium and olodaterol—used as a maintenance treatment for chronic obstructive pulmonary disease (COPD). It helps relax the muscles around the airways, making it easier to breathe and reducing COPD symptoms like shortness of breath and wheezing. This medication is not intended for immediate relief of sudden breathing problems.
Stiolto is a once-daily inhaler combining two bronchodilators for long-term maintenance treatment of COPD symptoms.
Key facts at a glance
- RxNorm
- 1651267
- Generic
- Stiolto
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Stiolto is indicated for the maintenance treatment of COPD, including chronic bronchitis and emphysema. It helps reduce flare-ups and improve breathing in adults with COPD but is not used for asthma or acute bronchospasm.
Stiolto contains two active ingredients: tiotropium (a long-acting muscarinic antagonist) and olodaterol (a long-acting beta2-adrenergic agonist). Together, they relax and widen the airways by targeting different pathways, making it easier to move air in and out of the lungs.
Stiolto is typically inhaled once daily using the Respimat inhaler. Common side effects may include cough, dry mouth, and upper respiratory tract infections. Patients should not use it for acute symptoms and should seek medical attention if their breathing worsens. It may interact with other anticholinergic or beta-agonist medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy