Streptococcus Pneumoniae Serotype 10A Conjugate Vaccine
This vaccine targets Streptococcus pneumoniae serotype 10a, a bacterium responsible for serious infections like pneumonia, meningitis, and bloodstream infections. It is a conjugate vaccine that links the capsular polysaccharide antigen of serotype 10a to the CRM197 protein (a nontoxic diphtheria toxin mutant) to enhance immune response, particularly in populations like infants who respond poorly to polysaccharide antigens alone. While many pneumococcal vaccines cover multiple serotypes, this vaccine specifically addresses serotype 10a, which is included in some broader pneumococcal conjugate vaccine formulations.
A conjugate vaccine designed to prevent Streptococcus pneumoniae serotype 10a infections by training the immune system to recognize the bacterium's capsular polysaccharide.
Key facts at a glance
- RxNorm
- 2566291
- Generic
- Streptococcus Pneumoniae Serotype 10a Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, and otitis media caused by Streptococcus pneumoniae serotype 10a. May be used in pediatric populations or specific high-risk groups depending on regional recommendations and vaccine formulation.
The vaccine contains the capsular polysaccharide antigen from S. pneumoniae serotype 10a, chemically conjugated to CRM197 protein. This conjugation converts the immune response from T-cell independent (typical of polysaccharides alone) to T-cell dependent, producing stronger and more durable antibody responses with immunological memory.
Like other pneumococcal conjugate vaccines, this may be administered as part of combination formulations covering multiple serotypes. Common side effects include injection site reactions, fever, and irritability. Contraindications include severe allergic reaction to any vaccine component. Efficacy and specific dosing schedules depend on the target population and regulatory approvals in specific countries.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy