Streptococcus Pneumoniae Serotype 15B Conjugate Vaccine
This vaccine provides immunization against Streptococcus pneumoniae serotype 15b, a bacterial strain that can cause serious infections like pneumonia, meningitis, and bloodstream infections. It works by training the immune system to recognize the capsular antigen of serotype 15b, helping prevent pneumococcal disease in vaccinated individuals.
A conjugate vaccine targeting pneumococcal serotype 15b for prevention of associated invasive bacterial infections.
Key facts at a glance
- RxNorm
- 2566294
- Generic
- Streptococcus Pneumoniae Serotype 15b Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, and bacteremia caused by Streptococcus pneumoniae serotype 15b. May be used in populations at risk for pneumococcal infections, though specific age indications depend on the particular vaccine formulation.
The vaccine contains capsular antigens from S. pneumoniae serotype 15b conjugated to diphtheria CRM197 protein, which serves as a carrier to enhance immune response. This conjugation helps the immune system mount a stronger antibody response, particularly in young children whose immune systems may not respond adequately to polysaccharide antigens alone.
Common adverse effects may include injection site reactions, fever, and irritability. The vaccine is contraindicated in individuals with known hypersensitivity to any vaccine component. As with all vaccines, it may not provide complete protection in all recipients, and the specific serotype coverage is limited to serotype 15b only.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy