Streptococcus Pneumoniae Serotype 16F Conjugate Vaccine
This is a pneumococcal conjugate vaccine targeting Streptococcus pneumoniae serotype 16f. The vaccine consists of capsular polysaccharides from serotype 16f conjugated to diphtheria CRM197 protein to enhance immunogenicity. It is designed to provide protection against pneumococcal disease caused specifically by serotype 16f bacteria.
A pneumococcal conjugate vaccine targeting serotype 16f using diphtheria CRM197 protein as a carrier to prevent pneumococcal infections.
Key facts at a glance
- RxNorm
- 2686918
- Generic
- Streptococcus Pneumoniae Serotype 16f Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, and other infections caused by Streptococcus pneumoniae serotype 16f. May be used in populations at risk for pneumococcal infections where this serotype is relevant.
The vaccine contains purified capsular polysaccharides from S. pneumoniae serotype 16f chemically linked to diphtheria CRM197 protein. This conjugation converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, enhancing immune response and inducing better immunological memory, particularly in young children.
This is a serotype-specific vaccine and does not provide protection against other pneumococcal serotypes. Safety and immunogenicity data specific to this formulation should be consulted. Like other conjugate vaccines, it may be used in populations where plain polysaccharide vaccines are less effective, such as young children or immunocompromised individuals.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy