Streptococcus Pneumoniae Serotype 18C Conjugate Vaccine
This is a pneumococcal conjugate vaccine that provides protection against Streptococcus pneumoniae serotype 18c. The vaccine works by conjugating the capsular polysaccharide of serotype 18c to the diphtheria CRM197 protein, which enhances immune response especially in young children. It is used as part of pneumococcal immunization strategies to prevent invasive pneumococcal disease, pneumonia, and otitis media caused by this serotype.
A conjugate vaccine targeting pneumococcal serotype 18c using diphtheria CRM197 protein as a carrier to prevent pneumococcal infections.
Key facts at a glance
- RxNorm
- 798222
- Generic
- Streptococcus Pneumoniae Serotype 18c Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Prevnar 13
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, and otitis media caused by Streptococcus pneumoniae serotype 18c. Used in pediatric immunization programs.
The vaccine contains the capsular polysaccharide antigen from S. pneumoniae serotype 18c conjugated to diphtheria CRM197 protein carrier. This conjugation converts a T-cell independent antigen into a T-cell dependent antigen, enhancing immunogenicity and inducing immunological memory, particularly important in infants and young children.
This is a serotype-specific vaccine and does not provide protection against other pneumococcal serotypes. Part of a broader conjugate vaccine strategy that may include multiple serotypes. Standard contraindications include severe allergic reaction to any vaccine component. Administered according to national immunization schedules.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy