Streptococcus Pneumoniae Serotype 19A Conjugate Vaccine
This is a monovalent pneumococcal conjugate vaccine targeting Streptococcus pneumoniae serotype 19A, a leading cause of invasive pneumococcal disease. The vaccine works by stimulating the immune system to produce protective antibodies against the capsular polysaccharide of serotype 19A, which is conjugated to CRM197 (a nontoxic diphtheria toxin mutant) to enhance immune response, particularly in young children.
A conjugate vaccine targeting pneumococcal serotype 19A to prevent serious infections such as pneumonia and meningitis.
Key facts at a glance
- RxNorm
- 901624
- Generic
- Streptococcus Pneumoniae Serotype 19a Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Capvaxive, Prevnar 13
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 19A, including pneumonia, meningitis, bacteremia, and otitis media. Serotype 19A is particularly associated with antibiotic-resistant infections.
The vaccine contains capsular polysaccharides from serotype 19A covalently linked to CRM197 carrier protein, which converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, enhancing immunogenicity and immunological memory, especially in pediatric populations.
This monovalent conjugate vaccine utilizes the same platform technology as other pneumococcal conjugate vaccines (PCV13, PCV15, PCV20) which cover multiple serotypes including 19A. Administration follows standard immunization schedules. As with all vaccines, contraindications include severe allergic reactions to any vaccine component.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy