Streptococcus Pneumoniae Serotype 19F Conjugate Vaccine
This is a pneumococcal conjugate vaccine that protects against Streptococcus pneumoniae serotype 19F by conjugating the capsular polysaccharide antigen to a diphtheria CRM197 protein carrier. The protein conjugation enhances immune response, making it effective for immunization against pneumococcal diseases in children and other at-risk populations.
A conjugate vaccine providing targeted protection against pneumococcal serotype 19F infections, particularly useful in pediatric populations.
Key facts at a glance
- RxNorm
- 798224
- Generic
- Streptococcus Pneumoniae Serotype 19f Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Prevnar 13
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, and otitis media caused by Streptococcus pneumoniae serotype 19F. Primarily used in infant and childhood immunization programs, though may also be indicated for other at-risk groups depending on specific national guidelines.
The vaccine works by presenting the pneumococcal capsular polysaccharide antigen (19F) chemically linked to the diphtheria CRM197 protein carrier. This conjugation converts a T-cell independent antigen into a T-cell dependent antigen, enabling a stronger and more durable immune response with enhanced immunological memory, particularly important in young children whose immune systems respond poorly to pure polysaccharide vaccines.
Like all vaccines, effectiveness varies by individual immune response. Contraindications include severe allergic reactions to any vaccine component. May cause common vaccination side effects such as fever, injection site reactions, or irritability in pediatric use. This description covers the general class of 19F-containing conjugate vaccines; specific product information should be consulted for individual preparations.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy