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Streptococcus Pneumoniae Serotype 23A Conjugate Vaccine

Published: July 26, 2026Updated: August 31, 2026

This vaccine provides targeted immunization against Streptococcus pneumoniae serotype 23a, a bacterial strain that can cause serious invasive diseases including pneumonia and meningitis. The vaccine uses capsular antigen conjugated to diphtheria CRM197 protein, an approach that enhances immune response by converting a T-cell independent antigen into a T-cell dependent one.

Quick summary

A conjugate vaccine targeting pneumococcal serotype 23a infection prevention.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 31, 2026Editorial policy

Key facts at a glance

RxNorm
2686921
Generic
Streptococcus Pneumoniae Serotype 23a Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
Class
unclassified
Brands
Capvaxive
Availability
rx
Lactation
unknown
Routes
—
Forms
prefilled syringe
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention of invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 23a, including pneumonia, bacteremia, and meningitis. May be used in populations at high risk for specific pneumococcal serotypes.

Stimulates production of protective antibodies against the capsular polysaccharide of S. pneumoniae serotype 23a. The CRM197 carrier protein enhances immunogenicity by promoting T-cell dependent antibody responses, making it effective in populations like infants who respond poorly to unconjugated polysaccharides.

Part of targeted serotype-specific vaccination strategies. As with all vaccines, effectiveness depends on individual immune response. Standard contraindications for vaccine hypersensitivity apply. Should be administered according to age-appropriate schedules and risk-based recommendations.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy