Streptococcus Pneumoniae Serotype 23F Conjugate Vaccine
This vaccine provides targeted protection against Streptococcus pneumoniae serotype 23f, a bacterial strain known to cause serious infections like pneumonia, meningitis, and bloodstream infections. By conjugating the capsular antigen to diphtheria CRM197 protein, it enhances immune response, making it particularly effective for immunocompromised patients and young children who may not respond well to plain polysaccharide vaccines.
A conjugate vaccine that protects against pneumococcal disease caused by serotype 23f by using a diphtheria protein carrier to boost immune response.
Key facts at a glance
- RxNorm
- 798226
- Generic
- Streptococcus Pneumoniae Serotype 23f Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Prevnar 13
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, bacteremia, and meningitis specifically caused by Streptococcus pneumoniae serotype 23f. May be used as part of a comprehensive pneumococcal immunization strategy for at-risk populations.
The vaccine contains purified capsular polysaccharide from serotype 23f bacteria chemically linked to CRM197, a nontoxic mutant of diphtheria toxin. This conjugation converts a T-cell independent antigen into a T-cell dependent one, enabling stronger antibody production and immunological memory.
Administered by intramuscular injection according to age-appropriate schedules. Contraindicated in individuals with known hypersensitivity to any vaccine components. May be used alongside other pneumococcal vaccines targeting different serotypes. Immunocompromised patients may require additional doses per physician recommendations.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy