Streptococcus Pneumoniae Serotype 31 Conjugate Vaccine
This is a specialized pneumococcal conjugate vaccine that provides active immunization against Streptococcus pneumoniae serotype 31, a bacterial strain associated with invasive pneumococcal disease. The vaccine works by conjugating capsular polysaccharides from serotype 31 to the CRM197 carrier protein, a non-toxic mutant of diphtheria toxin, to enhance immune response and generate immunological memory.
A conjugate vaccine targeting pneumococcal serotype 31 that links bacterial capsular antigens to a diphtheria protein carrier to improve vaccine efficacy.
Key facts at a glance
- RxNorm
- 2686924
- Generic
- Streptococcus Pneumoniae Serotype 31 Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, and bloodstream infections caused by S. pneumoniae serotype 31. May be used in specific populations at risk for this serotype, including children and immunocompromised individuals.
The vaccine contains purified capsular polysaccharides from serotype 31 conjugated to CRM197 protein. This conjugation converts T-cell independent polysaccharide antigens into T-cell dependent antigens, producing stronger antibody responses and immunological memory.
Conjugate technology allows effective immunization in young children who respond poorly to polysaccharide-only vaccines. Adverse effects typically include injection site reactions, fever, and fatigue. This vaccine targets a less common serotype not included in standard childhood pneumococcal conjugate vaccines.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy