Streptococcus Pneumoniae Serotype 33F Conjugate Vaccine
This is a pneumococcal conjugate vaccine targeting Streptococcus pneumoniae serotype 33f. The vaccine works by linking capsular antigens from the bacteria to a diphtheria CRM197 protein carrier, which helps enhance immune response, particularly in young children who typically have weaker responses to polysaccharide antigens alone. Such vaccines are used to help prevent invasive pneumococcal disease caused by covered serotypes.
A conjugate vaccine targeting pneumococcal serotype 33f that works by linking bacterial capsular antigens to a protein carrier to improve immune protection.
Key facts at a glance
- RxNorm
- 2566296
- Generic
- Streptococcus Pneumoniae Serotype 33f Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease (including bacteremia, meningitis, and severe pneumonia) caused by Streptococcus pneumoniae serotype 33f. Conjugate vaccines like this are primarily used in pediatric populations and high-risk individuals who need protection against specific pneumococcal serotypes.
The vaccine contains purified capsular polysaccharides from S. pneumoniae serotype 33f, which are chemically conjugated to diphtheria CRM197 protein. This conjugation converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, producing stronger and longer-lasting immune responses, particularly in young children whose immune systems respond poorly to polysaccharide antigens alone.
As a conjugate vaccine containing diphtheria protein carrier, this is typically administered intramuscularly. Standard childhood pneumococcal vaccines (like PCV13, PCV15, PCV20) cover different serotype combinations; this serotype 33f formulation addresses specific coverage needs. Administration should follow established immunization schedules, and contraindications include severe allergic reactions to any vaccine component. Medical supervision is required for appropriate patient selection and timing.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy