Streptococcus Pneumoniae Serotype 8 Conjugate Vaccine
This vaccine provides immunization against Streptococcus pneumoniae serotype 8, a bacterial pathogen responsible for serious infections such as pneumonia, meningitis, and bloodstream infections. It is a conjugate vaccine that links the capsular polysaccharide antigen of serotype 8 to a diphtheria CRM197 protein carrier to enhance immune response.
A conjugate vaccine targeting pneumococcal serotype 8 infections, using a diphtheria protein carrier to improve immune protection.
Key facts at a glance
- RxNorm
- 2566295
- Generic
- Streptococcus Pneumoniae Serotype 8 Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, and other serious infections caused by Streptococcus pneumoniae serotype 8. This serotype is among those included in broader pneumococcal vaccination strategies for populations at risk of pneumococcal infections.
The vaccine works by presenting the capsular polysaccharide antigen from S. pneumoniae serotype 8 conjugated to the diphtheria CRM197 protein. This conjugation converts a T-cell independent antigen into a T-cell dependent antigen, resulting in stronger and longer-lasting antibody responses, particularly in young children and immunocompromised individuals.
Conjugate vaccines like this one generally offer better immunogenicity than polysaccharide vaccines alone, especially in populations with less mature immune systems. Administration should follow standard vaccination schedules and contraindications. Specific dosing, scheduling, and target populations should be determined based on clinical guidelines and individual patient factors.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy