Streptococcus Pneumoniae Serotype 9N Conjugate Vaccine
This is a conjugate vaccine providing active immunization against Streptococcus pneumoniae serotype 9n. The vaccine works by linking pneumococcal capsular polysaccharides to a diphtheria CRM197 protein carrier, which enhances the immune response by converting it from a T-cell independent to a T-cell dependent response. It is designed to prevent pneumococcal diseases including pneumonia, meningitis, and otitis media caused specifically by serotype 9n.
A conjugate vaccine targeting pneumococcal serotype 9n using diphtheria CRM197 protein carrier technology to stimulate protective immunity against related infections.
Key facts at a glance
- RxNorm
- 2686926
- Generic
- Streptococcus Pneumoniae Serotype 9n Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Capvaxive
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, and otitis media caused by Streptococcus pneumoniae serotype 9n. May be used in populations where protection against this specific serotype is desired.
The pneumococcal capsular polysaccharide antigen for serotype 9n is chemically conjugated to diphtheria CRM197 protein, a non-toxic mutant of diphtheria toxin. This conjugation converts the immune response from T-cell independent to T-cell dependent, resulting in stronger and longer-lasting immunity with enhanced memory B-cell formation.
Conjugate vaccines like this one are particularly effective in young children whose immune systems respond poorly to polysaccharide antigens alone. The CRM197 carrier protein helps prime the immune system for a robust response. Standard contraindications include severe allergic reaction to any vaccine component. As with all vaccines, protection may not be complete in all recipients.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy