Streptococcus Pneumoniae Serotype 9V Conjugate Vaccine
This is a pneumococcal conjugate vaccine that provides protection against Streptococcus pneumoniae bacteria, specifically serotype 9v. The vaccine works by attaching the bacterial capsular antigen to a nontoxic diphtheria protein carrier (CRM197), which enhances immune response, particularly in young children whose immune systems don't respond well to polysaccharide antigens alone.
A conjugate vaccine that protects against pneumococcal disease caused by serotype 9v by using a diphtheria protein carrier to enhance immune response.
Key facts at a glance
- RxNorm
- 798232
- Generic
- Streptococcus Pneumoniae Serotype 9v Capsular Antigen Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Prevnar 20, Vaxneuvance, Prevnar 13
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive pneumococcal disease, pneumonia, meningitis, bacteremia, sinusitis, and acute otitis media caused by Streptococcus pneumoniae serotype 9v. May be used in infants, toddlers, and children as part of routine immunization schedules or for high-risk individuals.
The vaccine contains purified capsular polysaccharides from serotype 9v conjugated to CRM197, a nontoxic mutant of diphtheria toxin. This conjugation converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, producing stronger and longer-lasting immune responses with enhanced memory B-cell formation.
As with all vaccines, complete protection requires adherence to the recommended dosing schedule. Contraindications include severe allergic reactions to any vaccine component. Common side effects may include injection site reactions, fever, and irritability. Efficacy varies based on individual immune response and circulating serotypes.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 30, 2026. · Read our editorial policy