Buprenorphine and Naloxone
Suboxone is a brand-name medication combining buprenorphine and naloxone, used primarily for medication-assisted treatment of opioid use disorder. It helps reduce cravings and withdrawal symptoms while the naloxone component discourages misuse by causing withdrawal if injected.
Suboxone is used to treat opioid dependence by reducing withdrawal symptoms and cravings.
Key facts at a glance
- RxNorm
- 352990
- Generic
- Suboxone
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Suboxone is indicated for the treatment of opioid use disorder (OUD) in adults. It is used as part of a complete treatment program that includes counseling and behavioral therapy. The medication helps individuals reduce or stop the use of opioids and can be used for both induction (initial treatment) and maintenance phases of recovery.
Suboxone contains two active ingredients: buprenorphine, a partial opioid agonist that binds to the same receptors as opioids but produces weaker effects, helping to reduce cravings and withdrawal symptoms; and naloxone, an opioid antagonist that blocks the effects of opioids. When taken as directed sublingually, naloxone has minimal effect, but if the medication is misused by injection, the naloxone becomes active and can precipitate withdrawal symptoms.
Suboxone should be prescribed and managed by healthcare providers experienced in addiction medicine. Patients should not discontinue use abruptly without medical guidance. It carries risks of dependence and should be stored securely. The medication may cause side effects such as headache, nausea, or drowsiness. Patients should inform their doctor of all other medications and substances they are taking, as dangerous interactions can occur.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy