Sucralfate
Sucralfate is a cytoprotective medication that forms a protective barrier over ulcers and irritated tissue in the stomach and esophagus.
Sucralfate protects the lining of the stomach and intestines by forming a coating over ulcers and damaged tissue.
Key facts at a glance
- ATC
- A02BX02
- RxNorm
- 10156
- Generic
- Sucralfate
- Class
- atc-a02
- Brands
- Carafate
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, suspension
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sucralfate is used to treat active gastric and duodenal ulcers, maintain healing of duodenal ulcers, and manage gastroesophageal reflux disease (GERD). It may also be used for stress ulcer prophylaxis in hospitalized patients.
Sucralfate binds to exposed proteins in ulcerated tissue, forming a viscous, adhesive coating that acts as a physical barrier against stomach acid, pepsin, and bile salts. It may also stimulate bicarbonate and prostaglandin secretion to promote mucosal defense.
Take on an empty stomach, typically 1 hour before meals and at bedtime. Sucralfate can reduce absorption of other medications, so spacing doses is recommended. Use with caution in patients with renal impairment due to aluminum content. Common side effects include constipation and dry mouth.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy