Phenylephrine
Sudafed PE is a brand-name over-the-counter nasal decongestant used to temporarily relieve sinus pressure and nasal congestion caused by allergies, colds, or the flu. It contains phenylephrine as its active ingredient and is intended for short-term use in adults and children above a certain age.
Sudafed PE is a nasal decongestant that relieves stuffy nose and sinus pressure from colds or allergies.
Key facts at a glance
- RxNorm
- 603256
- Generic
- Sudafed Pe
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves nasal congestion, sinus pressure, and congestion in the nasal passages due to the common cold, hay fever, or other upper respiratory allergies.
Contains phenylephrine, an alpha-adrenergic agonist that causes vasoconstriction (narrowing) of blood vessels in the nasal passages, reducing swelling and congestion.
For short-term use only (typically 3-5 days). Consult a healthcare provider before use if you have heart disease, high blood pressure, diabetes, thyroid problems, or are taking other medications. Do not use if you are currently taking MAO inhibitors. Not recommended for children under certain ages without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy