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Sulfadimethoxine

Published: July 26, 2026Updated: August 25, 2026

Sulfadimethoxine is a long-acting sulfonamide antibiotic used to treat various bacterial infections by inhibiting folic acid synthesis in susceptible organisms. It is primarily indicated for respiratory tract infections, urinary tract infections, and certain gastrointestinal infections caused by susceptible bacteria.

Quick summary

Sulfadimethoxine is a long-acting sulfonamide antibiotic used to treat bacterial infections by inhibiting folic acid synthesis in pathogens.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
J01ED01
RxNorm
10172
Generic
Sulfadimethoxine
Class
atc-j01
Brands
Sulfamed, Albon
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet, solution, suspension
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats respiratory tract infections, urinary tract infections, otitis media, and gastrointestinal infections caused by susceptible gram-positive and gram-negative bacteria. May also be used for certain protozoal infections like coccidiosis.

Sulfadimethoxine is a competitive antagonist of para-aminobenzoic acid (PABA), inhibiting bacterial dihydropteroate synthetase. This blocks folic acid synthesis, preventing bacterial DNA replication and growth.

Contraindicated in patients with sulfonamide hypersensitivity, severe renal impairment, or during late pregnancy. May cause crystalluria, blood dyscrasias, or photosensitivity. Adequate fluid intake is recommended. Cross-reactivity with other sulfonamides may occur.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy