Sulfaguanidine
Sulfaguanidine is a sulfonamide antibiotic with local action in the gastrointestinal tract, used as an intestinal antiseptic for bacterial dysentery and infections.
Sulfaguanidine is an older sulfonamide antibiotic used as an intestinal antiseptic for treating gastrointestinal infections like bacillary dysentery.
Key facts at a glance
- ATC
- A07AB03
- RxNorm
- 10174
- Generic
- Sulfaguanidine
- Class
- atc-a07
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Bacillary dysentery and other intestinal bacterial infections; used as a bowel antiseptic before gastrointestinal surgery. This medication has largely been replaced by more modern antibiotics in clinical practice.
Sulfaguanidine is a sulfonamide antibiotic that inhibits bacterial synthesis of folic acid by competing with para-aminobenzoic acid (PABA). It acts primarily in the intestinal lumen with minimal systemic absorption.
Contraindicated in patients with sulfonamide allergy. Adequate fluid intake is recommended to prevent crystalluria. Due to limited systemic absorption, it has largely been superseded by more effective and better-tolerated antibiotics for intestinal infections.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy