Sulfamethizole
Sulfamethizole is a sulfonamide-type antibiotic used primarily to treat urinary tract infections. It works by inhibiting bacterial growth through interference with folic acid synthesis, making it effective against susceptible gram-negative and gram-positive bacteria. This medication is typically prescribed for acute and recurrent urinary tract infections.
Sulfamethizole is an antibiotic sulfonamide used to treat urinary tract infections by inhibiting bacterial folate synthesis.
Key facts at a glance
- ATC
- B05CA04
- RxNorm
- 10179
- Generic
- Sulfamethizole
- Class
- atc-b05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used to treat urinary tract infections (both acute and recurrent), including cystitis and pyelonephritis. May also be used for respiratory tract infections and as part of prophylactic regimens in certain surgical procedures.
As a sulfonamide antibiotic, sulfamethizole inhibits bacterial dihydropteroate synthase, an enzyme essential for folic acid synthesis. This blocks bacterial DNA replication and protein synthesis, preventing growth and replication of susceptible organisms.
Patients with sulfonamide allergy, porphyria, or severe renal impairment should avoid this medication. Adequate fluid intake is essential to prevent crystalluria. May cause photosensitivity reactions and interactions with anticoagulants. Not recommended during late pregnancy or in newborns due to potential kernicterus risk.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy