Mafenide
Sulfamylon (mafenide acetate) is a topical antibacterial medication used to prevent and treat bacterial infections in burn wounds, particularly second and third-degree burns. It is applied directly to the burn site and helps reduce the risk of wound infection and sepsis during the healing process. This medication is typically used in hospital settings under medical supervision.
Sulfamylon is a topical antibiotic cream used to prevent and treat bacterial infections in burn wounds.
Key facts at a glance
- RxNorm
- 258054
- Generic
- Sulfamylon
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sulfamylon is used to prevent and treat bacterial infections in second and third-degree burn wounds. It is applied topically to burn sites to reduce the risk of sepsis and wound complications during the healing process.
As a topical sulfonamide antibiotic, Sulfamylon inhibits bacterial growth on the wound surface. It also has carbonic anhydrase inhibitory properties that may contribute to its antibacterial effectiveness in burn wound care.
Contraindicated in patients with sulfa allergies. May cause metabolic acidosis due to carbonic anhydrase inhibition, especially with prolonged use over large body surface areas. Use should be discontinued if signs of hypersensitivity or worsening infection occur. For external use only on burn wounds.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy