Sulindac
Sulindac is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce pain, inflammation, and stiffness caused by various inflammatory conditions. It is primarily prescribed for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis.
Sulindac is an NSAID used to treat inflammatory conditions like arthritis and gout by reducing pain and swelling.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- M01AB02
- RxNorm
- 10237
- Generic
- Sulindac
- Class
- atc-m01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sulindac is used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, and acute painful shoulder (bursitis/tendinitis). It helps manage pain, swelling, and stiffness associated with these conditions.
Sulindac works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins—chemicals in the body that cause pain, inflammation, and fever.
Like other NSAIDs, sulindac may increase the risk of heart attack, stroke, and gastrointestinal bleeding. It should be used at the lowest effective dose for the shortest duration. Patients with kidney problems should use caution, as sulindac and its metabolites are primarily eliminated by the kidneys.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy