Sunosi
Sunosi (solriamfetol) is a wakefulness-promoting medication used to treat excessive daytime sleepiness in adults with narcolepsy or obstructive sleep apnea (OSA). It works as a dopamine and norepinephrine reuptake inhibitor (DNRI), helping to increase alertness and reduce fatigue. This prescription medication is typically used when first-line treatments have not provided adequate symptom relief.
Sunosi is a prescription wakefulness agent used to combat excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea.
Key facts at a glance
- RxNorm
- 2121759
- Generic
- Sunosi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sunosi is indicated for the treatment of excessive daytime sleepiness in adults with narcolepsy or obstructive sleep apnea (OSA). It helps improve wakefulness and reduce feelings of fatigue during the day.
Sunosi contains solriamfetol, which acts as a dopamine and norepinephrine reuptake inhibitor (DNRI). By increasing the availability of these neurotransmitters in the brain, it promotes wakefulness and alertness.
Sunosi may increase blood pressure and heart rate; cardiovascular assessment is recommended before and during treatment. It has abuse potential and should be used with caution in patients with a history of substance abuse. Common side effects include headache, nausea, anxiety, and insomnia. Patients with serious heart problems should generally avoid this medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy