Granisetron
Sustol is a prescription anti-nausea medication containing granisetron as its active ingredient. It is administered as a subcutaneous (under-the-skin) extended-release injection to help prevent acute and delayed nausea and vomiting associated with chemotherapy treatments. This medication is typically given prior to chemotherapy to provide protection against treatment-induced nausea and vomiting.
Sustol is an anti-nausea injection used to prevent chemotherapy-induced nausea and vomiting.
Key facts at a glance
- RxNorm
- 1810485
- Generic
- Sustol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Sustol is used to prevent acute and delayed nausea and vomiting associated with initial and repeat courses of chemotherapy. It is specifically indicated for patients undergoing chemotherapy regimens that are known to cause significant nausea and vomiting.
Sustol contains granisetron, which belongs to a class of medications called 5-hydroxytryptamine 3 (5-HT3) receptor antagonists. It works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and vomiting responses.
Sustol is administered as a single subcutaneous injection by a healthcare professional. Common side effects may include headache, constipation, and injection site reactions. Patients should inform their healthcare provider about all medications they are taking and any history of heart conditions, as 5-HT3 antagonists may rarely cause heart rhythm changes. Pregnant or breastfeeding individuals should consult their doctor before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy