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Suvorexant

Published: July 26, 2026Updated: July 26, 2026

Suvorexant is a prescription medication used to treat insomnia in adults. It works by blocking orexin receptors in the brain, which reduces wakefulness and helps initiate and maintain sleep. The medication is typically taken at night, shortly before bedtime.

Quick summary

Suvorexant is an orexin receptor antagonist used to treat insomnia by promoting sleep onset and maintenance.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
N05CJ01
RxNorm
1547099
Generic
Suvorexant
Class
atc-n05
Brands
Belsomra
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of adult patients with insomnia characterized by difficulty with sleep onset and/or sleep maintenance.

Acts as an orexin receptor antagonist (OX1R and OX2R), blocking wake-promoting neuropeptides orexin A and orexin B from binding to their receptors. By inhibiting the orexin system, which plays a key role in promoting wakefulness, the medication helps facilitate sleep initiation and maintenance.

Take within 30 minutes before bedtime with at least 7 hours remaining before the intended wake time. May cause next-day drowsiness, dizziness, or impaired alertness. Contraindicated in patients with narcolepsy. Use caution when combining with other CNS depressants including alcohol. Requires prescription from a healthcare provider.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy