Dronabinol
Syndros is an oral solution containing dronabinol, a synthetic form of THC (the psychoactive component of cannabis). It is prescribed to treat nausea and vomiting in cancer chemotherapy patients who have not responded to other antiemetic treatments, and to stimulate appetite in patients with HIV/AIDS who have experienced significant weight loss. The medication works by acting on the endocannabinoid system in the body.
Syndros is a THC-based medication used to treat chemotherapy-induced nausea and stimulate appetite in HIV/AIDS patients with wasting syndrome.
Key facts at a glance
- RxNorm
- 1928949
- Generic
- Syndros
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Syndros is FDA-approved for two main uses: treating nausea and vomiting associated with cancer chemotherapy in patients who have not responded adequately to conventional antiemetic therapies, and stimulating appetite in patients with HIV/AIDS experiencing weight loss (cachexia).
Syndros contains dronabinol, a synthetic form of delta-9-tetrahydrocannabinol (THC). It works by binding to cannabinoid receptors (CB1 and CB2) in the body's endocannabinoid system, which plays a role in regulating nausea, vomiting, and appetite. This mechanism helps reduce chemotherapy-induced nausea and stimulates appetite.
Syndros is a Schedule III controlled substance due to its THC content and can cause psychoactive effects such as euphoria, dizziness, and paranoia. It should be used with caution in patients with a history of substance use disorders, mental health conditions, or cardiac disease. Common side effects include dry mouth, dizziness, and mood changes. Patients should avoid driving or operating machinery until they know how the medication affects them.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy