Lidocaine and Tetracaine
Synera is a topical anesthetic patch containing a combination of lidocaine and tetracaine that provides localized numbing of the skin. It is primarily used to reduce pain and discomfort associated with minor dermatological procedures and venipuncture. The patch is applied to the treatment area before the procedure to achieve temporary local anesthesia.
Synera is a lidocaine-tetracaine topical anesthetic patch used for temporary pain relief during minor medical procedures.
Key facts at a glance
- RxNorm
- 605343
- Generic
- Synera
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Synera is indicated for producing local dermal anesthesia prior to superficial dermatological procedures, including venipuncture, intravenous cannulation, and minor surgical procedures such as biopsies and electrosurgery.
Synera contains lidocaine and tetracaine, which block nerve signals in the skin by inhibiting sodium channels. This combination provides rapid and sustained local anesthetic effects, resulting in temporary numbing of the treated area.
Synera should only be applied to intact, unbroken skin and must be removed before procedures. It is not recommended for use on mucous membranes, broken skin, or on infants under 1 month of age. Patients should inform their healthcare provider of any allergies to local anesthetics. Application time typically ranges from 20 to 30 minutes for optimal effect.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy