Fostamatinib
Tavalisse (fostamatinib) is an oral spleen tyrosine kinase (Syk) inhibitor used to treat thrombocytopenia (low platelet count) in adults with chronic immune thrombocytopenia (ITP) who have had an insufficient response to other treatments. It works by blocking the Syk enzyme, which plays a key role in the immune-mediated destruction of platelets.
Tavalisse is an oral medication for adults with chronic immune thrombocytopenia (ITP) that raises platelet counts by inhibiting platelet destruction.
Key facts at a glance
- RxNorm
- 2044923
- Generic
- Tavalisse
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tavalisse is indicated for the treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous treatment.
Tavalisse is a spleen tyrosine kinase (Syk) inhibitor. It blocks the Syk enzyme, which is involved in the signaling pathway that leads to platelet destruction by macrophages, thereby helping to increase platelet counts.
Common side effects include hypertension, diarrhea, liver enzyme elevations, and neutropenia. Regular blood pressure monitoring and liver function tests are recommended during treatment. May cause fetal harm; effective contraception is advised. Available as an oral tablet taken with food.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy